Dacomitinib hydrate

Dacomitinib hydrate(PF-00299804, PF-804) is an orally administered, highly selective irreversible inhibitor targeting pan-ERBB receptors, with an IC50 of 6.0 nM for EGFR, 45.7 nM for ERBB2, and 73.7 nM for ERBB4. It also demonstrates anti-tumor activity.

Price Not Available 25mg Dacomitinib hydrate Supplier Page

Trivial name	PF-00299804, PF-804
Catalog Number	E4904
Molecular Formula	C21H28BN3O5
CAS#	1042385-75-0
Inchi	InChI=1S/C21H28BN3O5/c1-13(2)16(22(29)30)12-23-21(28)19(14(3)26)25-20(27)18-11-7-10-17(24-18)15-8-5-4-6-9-15/h4-11,13-14,16,19,26,29-30H,12H2,1-3H3,(H,23,28)(H,25,27)/t14-,16+,19+/m1/s1
Inchi Key	PPAJFLNVGDSLAB-ALKREAHSSA-N
SMILES	B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
Size	25mg
Supplier Page	http://www.selleckchem.com/products/dacomitinib-hydrate.html
Additional Information	https://file.selleck.cn/downloads/struct/E4904-Dacomitinib-hydrate-chemical-structure.png