Dantrolene
Dantrolene is an antagonist of ryanodine receptor (RYR) and a postsynaptic skeletal muscle relaxant that reduces calcium release from the sarcoplasmic reticulum (SR), leading to a dose-dependent decrease in myoplasmic free calcium levels. It is used to treat and control the accelerated hypermetabolism of skeletal muscle that leads to a malignant hyperthermia crisis.
| Trivial name | F368 |
| Catalog Number | E4902 |
| Molecular Formula | C16H15NO7S |
| CAS# | 7261-97-4 |
| Inchi | InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21) |
| Inchi Key | HWNUSGNZBAISFM-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/dantrolene.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4902-Dantrolene-chemical-structure.png |