Glafenine
Glafenine (Glafenin) is a non-steroidal anti-inflammatory drug (NSAID) and is a non-narcotic analgesic agent that not only acts as a proteostasis modulator but is also one of the most potent NSAID correctors of F508del-CFTR. It exhibits COX-2 inhibition in the arachidonic acid pathway and rescues class 2 CFTR mutants.
| Trivial name | Glafenin |
| Catalog Number | E4889 |
| Molecular Formula | C26H30FN7O3 |
| CAS# | 3820-67-5 |
| Inchi | InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,3 2,33) |
| Inchi Key | QYZOGCMHVIGURT-UHFFFAOYSA-N |
| SMILES | CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/glafenine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4889-Glafenine-chemical-structure.png |