Valbenazine
Valbenazine(Ingrezza, Mt-5199, NBI-98854, VBZ) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki of 110–190 nM. It is used to treat tardive dyskinesia and chorea associated with Huntington’s disease.
| Trivial name | Ingrezza, Mt-5199, NBI-98854, VBZ |
| Catalog Number | E4844 |
| Molecular Formula | C19H18N4O2 |
| CAS# | 1025504-45-3 |
| Inchi | InChI=1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+ |
| Inchi Key | DEZZLWQELQORIU-RELWKKBWSA-N |
| SMILES | C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/valbenazine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4844-Valbenazine-chemical-structure.png |