Simvastatin acid (ammonium)
Simvastatin acid (Tenivastatin) ammonium is a potent inhibitor of HMG-CoA reductase (HMGCR). Simvastatin acid ammonium also decreases Indoxyl sulfate-induced reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium regulates the expression of OATP3A1 in cardiomyocytes.
| Trivial name | Tenivastatin ammonium |
| Catalog Number | E4821 |
| Molecular Formula | C19H19FN4O3 |
| CAS# | 139893-43-9 |
| Inchi | InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1 |
| Inchi Key | WCWUXEGQKLTGDX-LLVKDONJSA-N |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/simvastatin-acid-ammonium.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4821-Simvastatin-acid-ammonium-chemical-structure.png |