Pemetrexed (disodium heptahydrate)
Pemetrexed (disodium heptahydrate) is a folate antimetabolite that inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase. It also induces apoptosis and cell-cycle arrest in non-small-cell lung cancer carrying an EGFR exon 19 deletion.
Catalog Number | E4818 |
Molecular Formula | C28H30CIN5O4S |
CAS# | 357166-29-1 |
Inchi | InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16- |
Inchi Key | FPYJSJDOHRDAMT-KQWNVCNZSA-N |
SMILES | CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/pemetrexed-disodium-heptahydrate.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4818-Pemetrexed-disodium-heptahydrate-chemical-structure.png |