Teneligliptin Hydrobromide Hydrate
Teneligliptin Hydrobromide Hydrate(MP-513 hydrobromide hydrate) is a potent, competitive, and long-lasting inhibitor of DPP-4. It competitively inhibited rhDPP-4, human plasma, and rat plasma with IC50 values of 0.889, 1.75, and 1.35 nM respectively. It suppresses high glucose-mediated mitochondrial dysfunction and can be used for treatment of type 2 diabetes.
Trivial name | MP-513 hydrobromide hydrate |
Catalog Number | E4814 |
Molecular Formula | C16H14BrN3O2.HCl |
CAS# | 1572583-29-9 |
Inchi | InChI=1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H |
Inchi Key | ZJOKWAWPAPMNIM-UHFFFAOYSA-N |
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/teneligliptin-hydrobromide-hydrate.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4814-Teneligliptin-Hydrobromide-Hydrate-chemical-structure.png |