Cu(II)-Elesclomol

Cu(II)-Elesclomol, a Cu2+ complex of Elesclomol, is a weak inhibitor of DNA topoisomerase I. It is also highly capable of inducing cuproptosis and apoptosis. It induces DNA double-strand breaks in K562 cells and causes a G1 cell cycle block. Cu(II)-Elesclomol displays anticancer activity.

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Catalog Number	E4801
Molecular Formula	C21H22Cl2FN5O
CAS#	1224195-72-5
Inchi	InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
Inchi Key	KTEIFNKAUNYNJU-GFCCVEGCSA-N
SMILES	CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
Size	1mg
Supplier Page	http://www.selleckchem.com/products/cu-ii-elesclomol.html
Additional Information	https://file.selleck.cn/downloads/struct/E4801-Cu-II-Elesclomol-chemical-structure.png