Adezmapimod hydrochloride

Adezmapimod hydrochloride (RWJ 64809 hydrochloride, SB 203580 hydrochloride) is an inhibitor of the MAPK family member termed as stress-activated protein kinase 2a(SAPK2a; also known as p38). It exhibits IC50 of SAPK2a/p38 and SAPK2b/p38β2 with IC50 values of 50 nM and 500 nM respectively and can be used in research of chronic inflammatory diseases, such as rheumatoid arthritis.

Price Not Available 5mg Adezmapimod hydrochloride Supplier Page

Trivial name	RWJ 64809 hydrochloride, SB 203580 hydrochloride
Catalog Number	E4791
Molecular Formula	C30H30Cl2N4O4
CAS#	869185-85-3
Inchi	InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)
Inchi Key	BDUHCSBCVGXTJM-UHFFFAOYSA-N
SMILES	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/adezmapimod-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E4791-Adezmapimod-hydrochloride-chemical-structure.png