4-DAMP
4-DAMP (4-diphenyl-acetoxy-N-methyl-piperidine) (4-DAMP methiodide) is a selective antagonist of M3 type muscarinic acetylcholine receptors (M3-mAChR) with a pKi of 9.3. It also has a high affinity for the closely-related M5 receptor with a pKi of 8.9. It is routinely used to study the regulation and functions of the M3 receptor.
Trivial name | 4-DAMP methiodide |
Catalog Number | E4774 |
Molecular Formula | C18H11BrN2O2 |
CAS# | 1952-15-4 |
SMILES | C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/4-damp.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4774-4-DAMP-chemical-structure.png |