4-DAMP
4-DAMP (4-diphenyl-acetoxy-N-methyl-piperidine) (4-DAMP methiodide) is a selective antagonist of M3 type muscarinic acetylcholine receptors (M3-mAChR) with a pKi of 9.3. It also has a high affinity for the closely-related M5 receptor with a pKi of 8.9. It is routinely used to study the regulation and functions of the M3 receptor.
| Trivial name | 4-DAMP methiodide |
| Catalog Number | E4774 |
| Molecular Formula | C14H21N3O.2HCl |
| CAS# | 1952-15-4 |
| Inchi | InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11-,12-;;/m1../s1 |
| Inchi Key | IDDDVXIUIXWAGJ-LJDSMOQUSA-N |
| SMILES | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/4-damp.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4774-4-DAMP-chemical-structure.png |