NX-13
Amelenodor (NX-13) is an orally available, gut-selective molecule that activates the mitochondrial receptor NLRX1 to reduce intestinal inflammation. It promotes oxidative phosphorylation while suppressing proinflammatory pathways like Th1/Th17 differentiation and cytokine production. It has the potential to treat inflammatory bowel disease (IBD).
| Trivial name | Amelenodor |
| Catalog Number | E4755 |
| Molecular Formula | C15H13N3S |
| CAS# | 2389235-01-0 |
| Inchi | InChI=1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18) |
| Inchi Key | KATNUHQNJGNLPW-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/nx-13.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4755-NX-13-chemical-structure.png |