BI-9787
BI-9787 is a potent zwitterion inhibitor of ketohexokinase(KHK) with IC50 values of 12 nM and 12.8 nM for hKHK-A and hKHK-C. It exhibits good metabolic stability in rat hepatocytes and serves as a potent tool compound for in vitro and in vivo studies in rodents.
| Catalog Number | E4744 |
| Molecular Formula | C16H14F3IN2O4 |
| CAS# | 3043939-18-7 |
| Inchi | InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1 |
| Inchi Key | SUDAHWBOROXANE-SECBINFHSA-N |
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/bi-9787.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4744-BI-9787-chemical-structure.png |