NDI-101150
NDI-101150 is a potent HPK1 (MAP4K1) inhibitor that selectively activates immune cells such as T cells, B cells, and dendritic cells. It significantly inhibits tumor growth and induces complete tumor regression in the EMT-6 mouse model.
| Catalog Number | E4726 |
| Molecular Formula | C29H31N7O.CH4SO3 |
| CAS# | 2628486-22-4 |
| Inchi | InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,3 3,34);1H3,(H,2,3,4) |
| Inchi Key | YLMAHDNUQAMNNX-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/ndi-101150.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4726-NDI-101150-chemical-structure.png |