KHK-6

KHK-6 is a potent ATP-competitive inhibitor of HPK1 kinase activity with an IC50 value of 20 nM. It significantly enhances CD3/CD28-induced production of cytokines by downregulating the HPK1-SLP-76 signaling cascade in the TCR signaling pathway.

Price Not Available 50mg KHK-6 Supplier Page

Catalog Number	E4710
Molecular Formula	C19H25BN4O4
Inchi	InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
Inchi Key	GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES	B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
Size	50mg
Supplier Page	http://www.selleckchem.com/products/khk-6.html
Additional Information	https://file.selleck.cn/downloads/struct/E4710-KHK-6-chemical-structure-tube.png