CMP-5
CMP5 is a potent and selective small molecule inhibitor of PRMT5. It is found to selectively block S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. It also exhibit potential for research into treatment for EBV+ lymphomas and other B-cell NHL subtypes.
| Catalog Number | E4701 |
| Molecular Formula | C19H16N2O5 |
| CAS# | 880813-42-3 |
| Inchi | InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23) |
| Inchi Key | YOZBGTLTNGAVFU-UHFFFAOYSA-N |
| SMILES | CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/cmp-5.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4701-CMP-5-chemical-structure.png |