Taminadenant
Taminadenant (NIR178, PBF509) is a non-xanthine and non-furan antagonist of adenosine A2A receptor (A2AR). It can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with Kb values of 72.8 nM and 8.2 nM, respectively. It exhibits potential utility for Parkinson’s disease (PD) treatment.
| Trivial name | NIR178, PBF509 |
| Catalog Number | E4632 |
| Molecular Formula | C28H29NO6 |
| CAS# | 1337962-47-6 |
| SMILES | COC1=CC(=CC(=C1)OC)\C=C\C2=CC=C(NC(=O)\C=C\C3=CC(=C(OC)C(=C3)OC)OC)C=C2 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/taminadenant.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4632-Taminadenant-chemical-structure.png |