Buloxibutid
Buloxibutid (AT2 Agonist C21) is a selective agonist of angiotensin II type 2 receptor (AT2R) with a Ki value of 0.4 nM for the AT2 receptor and a Ki >10 µM for the AT1 receptor. Its treatment significantly reduces vascular remodelling, improves hemodynamics, and decreases pulmonary collagen deposition in the Sugen-Hypoxia model of pulmonary hypertension.
Trivial name | AT2 Agonist C21 |
Catalog Number | E4616 |
Molecular Formula | C25H34N6O8S2 |
CAS# | 477775-14-7 |
SMILES | CC1=CC(=CC=C1)C=NNC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4.CS(=O)(=O)O.CS(=O)(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/buloxibutid.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4616-Buloxibutid-chemical-structure.png |