Irpagratinib
Irpagratinib (ABSK011) is a potent inhibitor of FGFR4 with an IC50 of < 10 nM in biochemical assays. It effectively suppresses FGFR4 auto-phosphorylation and disrupts downstream signal transduction. It also strongly inhibits tumor growth and induces regression in subcutaneous xenograft models.
| Trivial name | ABSK011 |
| Catalog Number | E1979 |
| CAS# | 2230974-62-4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/irpagratinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1979-Irpagratinib-chemical-structure.png |