Pebezertinib
Pebezertinib is a central nervous system (CNS)-penetrant, wild-type EGFR-sparing, covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM. It also exhibits a potent anti-tumor efficacy.
| Trivial name | LNG-451 |
| Catalog Number | E1877 |
| CAS# | 2769954-39-2 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/blu-451.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1877-BLU-451-LNG-451-chemical-structure.png |