Inixaciclib
Inixaciclib (NUV-422) is a potent inhibitor of CDK2, CDK4, and CDK6. It inhibits the growth of glioma cell lines in vitro and exhibits antitumor activity in GB xenograft models, PDX models of HR+ HER2- metastatic breast cancer resistant to CDK4/6 inhibitors and prostate cancer resistant to anti-androgens.
| Trivial name | NUV-422 |
| Catalog Number | E1863 |
| CAS# | 2370913-42-9 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/inixaciclib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1863-Inixaciclib-chemical-structure.png |