VU0463271
VU0463271 is a selective and potent antagonist of neuronal-specific potassium-chloride cotransporter 2 KCC2, with an IC50 of 61 nM. VU0463271 demonstrates over 100-fold selectivity compared to the closely related Na-K-2Cl cotransporter 1 (NKCC1).
| Catalog Number | E1632 |
| Molecular Formula | C11H9FN4O3 |
| CAS# | 1391737-01-1 |
| SMILES | COC(=O)C1=N[NH]C(=N1)NC(=O)C2=CC=C(F)C=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/vu0463271.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1632-VU0463271-chemical-structure.png |