RK-701
RK-701 is a highly selective, potent, and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM. RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in γ-globin induction. RK-701 is used in the research of sickle cell disease.
Catalog Number | E1607 |
Molecular Formula | C10H8O10S3 |
CAS# | 2648855-18-7 |
SMILES | OC1=CC(=CC2=CC(=CC(=C12)[S](O)(=O)=O)[S](O)(=O)=O)[S](O)(=O)=O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/rk-701.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1607-RK-701-chemical-structure.png |