Butyrolactone 3
Butyrolactone 3 is a non-irreversible inhibitor of the histone acetyltransferase Gcn5, with an IC50 of 100 μM. It selectively targets the Gcn5/PCAF family exhibiting weak inhibition of CBP HAT with an IC50 of 0.5 mM and also inhibits pre-mRNA splicing in vitro before catalysis, with an IC50 of 0.5 mM.
| Trivial name | MB-3 |
| Catalog Number | E1387 |
| Molecular Formula | C13H11N7O.3ClH |
| CAS# | 778649-18-6 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/butyrolactone-3.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1387-Butyrolactone-3-chemical-structure.png |