Tenapanor
Tenapanor (AZD1722, RDX5791) is a potent and orally active inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3). It exhibits an IC50 of 2 and 6 nM in human and mouse ileum monolayers, respectively. Tenapanor reduces intestinal phosphate absorption predominantly by reducing passive paracellular phosphate flux.
Trivial name | AZD1722, RDX5791 |
Catalog Number | E1186 |
Molecular Formula | C15H23NO2S |
CAS# | 1234423-95-0 |
SMILES | CCCN1CCC(CC1)C2=CC(=CC=C2)[S;v6](C)(=O)=O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/tenapanor.html |
Additional Information | https://file.selleck.cn/downloads/struct/E1186-Tenapanor-chemical-structure.png |