Tenapanor
Tenapanor (AZD1722, RDX5791) is a potent and orally active inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3). It exhibits an IC50 of 2 and 6 nM in human and mouse ileum monolayers, respectively. Tenapanor reduces intestinal phosphate absorption predominantly by reducing passive paracellular phosphate flux.
| Trivial name | AZD1722, RDX5791 |
| Catalog Number | E1186 |
| Molecular Formula | C8H9NO4 |
| CAS# | 1234423-95-0 |
| SMILES | Cl.NC(C(O)=O)C1=CC(=CC(=C1)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tenapanor.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1186-Tenapanor-chemical-structure.png |