SY-5609
SY-5609 (CDK7-IN-3) is an orally active and highly selective inhibitor of CDK7 with a KD value of 0.065 nM. SY-5609 exhibits poor inhibition on CDK2, CDK9, CDK12. SY-5609 displays antitumor activity and can induce apoptosis in tumor cells.
Trivial name | CDK7-IN-3 |
Catalog Number | E1041 |
Molecular Formula | C20H12F6N4O3 |
CAS# | 2417302-07-7 |
SMILES | FC(F)(F)C1=CC=C(C[N]2C=C(NC(=O)C3=NOC(=C3)C4=CC=CO4)C=N2)C(=C1)C(F)(F)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/sy-5609.html |
Additional Information | https://file.selleck.cn/downloads/struct/E1041-SY-5609-chemical-structure.png |