Lapatinib Ditosylate Monohydrate

A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2.

Catalog Number API388082788
Alternative Name(s) Lapatinib ditosylate hydrate LAPATINIB DITOSYLATE MONOHYDRATE Tykerb Tyverb
Research Area Anti-Tumor APIs
Molecular Formula C43H44ClFN4O11S3
CAS# 388082-78-8
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.O
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