Pemetrexed

Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2′-deoxyuridine-5′-monophosphate (dUMP) to 2′-deoxythymidine-5′-monophosphate (dTMP), an essential precursor in DNA synthesis.

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Catalog Number	INT137281233
Alternative Name(s)	Pemetrexed disodium Alimta LY231514
Research Area	Intermediates
Molecular Formula	C20H21N5O6
CAS#	137281-23-3
SMILES	C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
Size	inquiry
Supplier Page	https://www.protheragen-ing.com/pemetrexed-item-12053.html