Mevastatin/Compactin

A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite and an apoptosis inducer.

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Catalog Number INT73573883
Alternative Name(s) Compactin EC 700-442-0 Mevastatin ML-236B
Research Area Intermediates
Molecular Formula C23H34O5
CAS# 73573-88-3
SMILES CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O
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