Givosiran

Givosiran is a small interfering RNA targeting liver aminolevulinic acid synthase 1(ALAS1) messenger RNA.

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Catalog Number PIPB-0191
Alternative Name(s) ALN-AS1;21-[(2-Acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-N-[3-({5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanoyl}amino)propyl]-6-[(3-{[3-({5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy ]pentanoyl}amino)propyl]amino}-3-oxopropoxy)methyl]-6-({12-[(2R,4R)-4-hydroxy-2-methyl-1-pyrrolidinyl]-12-oxododecanoyl}amino)-11,17-dioxo-4,8-dioxa-12,16-diazahenicosan-1-amide
Research Area Oligonucleotides
Molecular Formula C78H139N11O30
CAS# 1639325-43-1
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Givosiran

Givosiran is a small interfering RNA that targets liver aminocellulose synthase 1 (ALAS1) messenger RNA, downregulates ALAS1 mRNA and prevents the accumulation of neurotoxic δ-aminofibrillary acid and porphyrins, and can be used in porphyria-related research. .

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Catalog Number API1639325431
Research Area Active Pharmaceutical Ingredients
CAS# 1639325-43-1
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Supplier Page https://www.protheragen-ing.com/givosiran-item-5963.html