TYM-3-98 | MedChemExpress (MCE)
TYM-3-98 is a selective inhibitor for PI3Kδ, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity[1].
| Trivial name | TYM-3-98 |
| Catalog Number | HY-163538 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | COC1=C(F)C=C(C2=NN(C(C)C3=NN(C4=CC=CC(S(C)(=O)=O)=C4)C5=CC(Cl)=CC=C53)C6=C2C(N)=NC=N6)C=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/tym-3-98.html |