J208 | MedChemExpress (MCE)

J208 is a dual inhibitor for histone deacetylase (HDAC) and DNA methyltransferase (DNMT). J208 inhibits proliferation of cancer cells, as well as the migration/invasion of TNBC. J208 induces apoptosis, arrests the cell cycle at G0/G1 phase. J2008 activates the innate immune signalling pathway in TNBC, by inducing the expression of endogenous retroviruses (ERVs)[1].

Trivial name J208
Catalog Number HY-163535
Research Area Inflammation/Immunology; Cancer
CAS# 2116468-11-0
Purity ≥98.0%
SMILES O=C1C=CN(C(N1)=O)CC2=CC=C(C=C2)C3=CN(N=N3)CCCCCCC(NO)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/j208.html