GZNL-P36 | MedChemExpress (MCE)
GZNL-P36 is an orally active inhibitor for SARS-CoV-2 papain-like protease (PLpro), with an IC50 of 6.45 nM. GZNL-P36 inhibits SARS-CoV and its variants with EC50 range from 58.2 nM to 2.66 μM. GZNL-P36 exhibits a peak plasma concentration Cmax of 549 ng/mL, a half-life T1/2 of 1.45 h and a bioavailability of 74.7% in CD-1 mouse. GZNL-P36 exhibits antiviral activity in SARS-CoV-2 XXB.1 infection in mouse[1].
| Trivial name | GZNL-P36 |
| Catalog Number | HY-162484 |
| Research Area | Infection |
| Purity | ≥98.0% |
| SMILES | CN1C2=CC=C(C3(CC3)NC(C4=CC(N5CC(C6)N(C)C6C5)=CC=C4C)=O)C7=C2C(C1=O)=CC=C7 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/gznl-p36.html |