BRD4/NAMPT-IN-1 | MedChemExpress (MCE)
BRD4/NAMPT-IN-1 (Compound A2) shows strong inhibitory effects on NAMPT and BRD4 (IC50=35 nM (NAMPT) and 58 nM (BRD4)). BRD4/NAMPT-IN-1 inhibits the growth and migration of hepatocellular carcinoma cells and promotes apoptosis. BRD4/NAMPT-IN-1 also shows potent anticancer effects in HCCLM3 xenograft mouse model, with no obvious toxic effects[1].
| Trivial name | BRD4/NAMPT-IN-1 |
| Catalog Number | HY-161515 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | ClC(C=C1)=CC=C1C2=N[C@@H](CC(NCCCNC(/C=C/C3=CN=CC=C3)=O)=O)C4=NN=C(C)N4C5=C2C(C)=C(C)S5 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/brd4-nampt-in-1.html |