hAChE/hBACE-1-IN-4 | MedChemExpress (MCE)
hAChE/hBACE-1-IN-4 (compound AK-2) is a quinazoline derivative. hAChE/hBACE-1-IN-4 shows significant inhibitory activity against hAChE and hBACE-1 enzymes (hAChE, IC50=0.283 μM; hBACE-1, IC50=0.231 μM). hAChE/hBACE-1-IN-4 has the potential to inhibit Aβ aggregation. hAChE/hBACE-1-IN-4 has non-neurotoxicity , blood-brain barrier permeability and oral activity. hAChE/hBACE-1-IN-4 can be used in Alzheimer’s disease research[1].
| Trivial name | hAChE/hBACE-1-IN-4 |
| Catalog Number | HY-161512 |
| Research Area | Neurological Disease |
| CAS# | 229476-71-5 |
| Purity | ≥98.0% |
| SMILES | COC1=C(OC)C=C2C(N(CC3)CCN3CC4=CC=CC=C4)=NC=NC2=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/hache-hbace-1-in-4.html |