Topovale | MedChemExpress (MCE)

Topovale (ARC 111) is a topoisomerase I inhbitor. Topovale is an antitumor agent, and shows low nM cytotoxicity against a panel of cancer cells. Topovale induces reversible topoisomerase I (TOP1) cleavage complexes in tumor cells[1].

Trivial name Topovale
Catalog Number HY-118942
Alternative Name(s) ARC 111
Research Area Cancer
CAS# 500214-53-9
Purity ≥98.0%
SMILES COC1=C(C=C(C2=C1)C(N(C3=C2C=NC4=C3C=C5OCOC5=C4)CCN(C)C)=O)OC
Size 1 mg
Supplier Page https://www.medchemexpress.com/topovale.html