CVN293 | MedChemExpress (MCE)

CVN293 is a selective and brain permeable potassium ion (K+) channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1β in microglia[1].

Trivial name CVN293
Catalog Number HY-158155
Research Area Inflammation/Immunology
CAS# 2815296-08-1
Purity ≥98.0%
SMILES NC1=NON=C1C2=NC3=CC=CC(F)=C3N2CC4=NN=CC=C4
Size 1 mg
Supplier Page https://www.medchemexpress.com/cvn293.html