NLRP3-IN-34 | MedChemExpress (MCE)

NLRP3-IN-34 (Compound T10) is an inhibitor for NLRP3 inflammasome. NLRP3-IN-34 inhibits ROS production, NLRP3 inflammasome-dependent IL-1β production (IC50 is 0.48 μM in cells J774A.1), and inhibits pyroptosis. NLRP3-IN-34 exhibits anti-inflammatory activity against DSS-induced peritonitis[1].

Trivial name NLRP3-IN-34
Catalog Number HY-158111
Research Area Inflammation/Immunology
CAS# 1392502-55-4
Purity ≥98.0%
SMILES CC1=COC2=C1C(C(C3=C2C=CC4=C3C(CCC4(C)C)OC(C5=C(C=CC=C5)O)=O)=O)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/nlrp3-in-34.html