PROTAC AR/AR-V7 degrader-1 | MedChemExpress (MCE)
PROTAC AR/AR-V7 degrader-1 (27c) is a PROTAC-based and dual AR, AR-V7 degrader, with DC50 values of 2.67 and 2.64 μM for AR and AR-V7, respectively. PROTAC AR/AR-V7 degrader-1 (27c) induces apoptosis (Red: AR antagonist; Blue: E3 ligase ligand; Black: linker)[1].
| Trivial name | PROTAC AR/AR-V7 degrader-1 |
| Catalog Number | HY-162412 |
| Research Area | Cancer |
| CAS# | 2841308-96-9 |
| Purity | ≥98.0% |
| SMILES | O=C1C(C)(C)N(CCNC2=C(C=CC=N3)C3=C(F)C=C2)C(N1C4=CC(C(F)(F)F)=C(C#N)C=C4)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/protac-ar-ar-v7-degrader-1.html |