KRASG12D-IN-3 | MedChemExpress (MCE)

KRASG12D-IN-3 is an orally active KRASG12D inhibitor that inhibits the cell growth of AGS and AsPC-1 cells with IC50 values of 0.38 nM and 1.23 nM, respectively (WO2024061370A1, compound Z1084)[1].

Trivial name KRASG12D-IN-3
Catalog Number HY-162445
Research Area Cancer
Purity ≥98.0%
SMILES ClC1=C(C(F)(F)F)C(C2=C(F)C(N=C(OC[C@]3(C/C(C4)=C(F)\F)N4CCC3)N=C5N(C[C@@H]6N[C@H]7CC6)[C@@H]7[C@H](C)O8)=C5C8=N2)=CC(N)=C1
Size 1 mg
Supplier Page https://www.medchemexpress.com/krasg12d-in-3.html