PROTAC NAMPT Degrader-1 | MedChemExpress (MCE)
PROTAC NAMPT Degrader-1 is a potent PROTAC targeting NAMPT with aDC50 value of 217 nM. PROTAC NAMPT Degrader-1 has anti-proliferative activity with an IC50 value of 0.12μM against A2780 cells.
(Srtucture Note: PINK, NAMPT activator (HY-163445); Blue, VHL ligand (HY-163440); Black, linker)[1].
Trivial name | PROTAC NAMPT Degrader-1 |
Catalog Number | HY-163440 |
Research Area | Cancer |
Purity | ≥98.0% |
SMILES | O=C(NCC1=CC=NC=C1)NC2=CC=C(C=C2)S(=O)(N3CCN(CC3)C(C4=CC=C(C=C4)/N=N/C5=C(N(N=C5C)CCCCC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C=C7)C8=C(N=CS8)C)C)=O)=O)=O)C)=O)=O |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/protac-nampt-degrader-1.html |