DCLK1-IN-5 | MedChemExpress (MCE)
DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis[1].
| Trivial name | DCLK1-IN-5 |
| Catalog Number | HY-161471 |
| Research Area | Inflammation/Immunology |
| CAS# | 3028774-14-0 |
| Purity | ≥98.0% |
| SMILES | O=S(C1=C(NC2=NC(NC3=C(OC)C=C(NC(N4CCN(C)CC4)=S)C=C3)=NC=C2Cl)C=CC=C1)(C(C)C)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/dclk1-in-5.html |