2′-Deoxyguanosine 5′-monophosphate disodium hydrate | MedChemExpress (MCE)
2′-Deoxyguanosine 5′-monophosphate (5′-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism)[1][2].
Trivial name | 2'-Deoxyguanosine 5'-monophosphate disodium hydrate |
Catalog Number | HY-145538 |
Alternative Name(s) | 5'-Deoxyguanylic acid disodium hydrate |
Research Area | Others |
CAS# | 146877-98-7 |
Purity | ≥98.0% |
SMILES | O[C@H]1C[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(O[Na])(O[Na])=O.[x].O |
Size | 100 mg |
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