2′-Deoxyguanosine 5′-monophosphate disodium hydrate | MedChemExpress (MCE)

2′-Deoxyguanosine 5′-monophosphate (5′-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism)[1][2].

Trivial name 2'-Deoxyguanosine 5'-monophosphate disodium hydrate
Catalog Number HY-145538
Alternative Name(s) 5'-Deoxyguanylic acid disodium hydrate
Research Area Others
CAS# 146877-98-7
Purity ≥98.0%
SMILES O[C@H]1C[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(O[Na])(O[Na])=O.[x].O
Size 50 mg
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