pan-KRAS-IN-9 | MedChemExpress (MCE)

pan-KRAS-IN-9 (Compound 52) is an inhibitor for in human tumor mutated genes KRAS, which inhibits proliferation of KRAS mutated cells AsPC-1 (G12D mutant) and SW480 (G12V mutant) with IC50 of 0.24 and 0.30 nM, respectively[1].

Trivial name pan-KRAS-IN-9
Catalog Number HY-162442
Research Area Cancer
Purity ≥98.0%
SMILES CO[C@@H](C)C(N=C1)=[C@@]([C@@]2=C(CC(C)(C)COC3=O)C4=CC(C5=CSC(C[C@H](NC([C@H]6[C@H](C)[C@@H]6C)=O)C(N7CCC[C@@H]3N7)=O)=N5)=CC=C4N2CC)C=C1C#CCN8CCN(C)CC8
Size 1 mg
Supplier Page https://www.medchemexpress.com/pan-kras-in-9.html