EBET-1055 | MedChemExpress (MCE)
EBET-1055 is a bromodomain and extra-terminal (BET) protein degrader (EBET) composed of a BET inhibitor (EBET-590, HY-161387), an E3 ubiquitin ligase ligand and connectors. EBET-1055 effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC). EBET-1055 also simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures[1].
| Trivial name | EBET-1055 |
| Catalog Number | HY-161346 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | OC[C@](OC1CC1)(C2=CC=CC=C2)C3=NC(N4CCC(CN5CCN(C(COC6=CC=CC(C(N7C8CCC(NC8=O)=O)=O)=C6C7=O)=O)CC5)CC4)=NC9=CC=C(C(C=C%10C)=CN(C)C%10=O)C=C93 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/ebet-1055.html |