AurkA allosteric-IN-1 | MedChemExpress (MCE)
AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor (IC50: 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA[1].
| Trivial name | AurkA allosteric-IN-1 |
| Catalog Number | HY-158038 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | O=C(C1=CC=CC(C2=CC=NC=C2)=C1)NCC3=CC4=C(OCO4)C=C3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/aurka-allosteric-in-1.html |