F44-A13 | MedChemExpress (MCE)
F44-A13 is an orally active and highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders[1].
| Trivial name | F44-A13 |
| Catalog Number | HY-163436 |
| Research Area | Metabolic Disease |
| CAS# | 1338190-14-9 |
| Purity | ≥98.0% |
| SMILES | CCN(C1=CC(OS(=O)(C2=CC=C(C=C2)NC(C)=O)=O)=C(C=C1)CN(C(NC(C)(C)C)=O)CC3CC3)CC |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/f44-a13.html |