PXB17 | MedChemExpress (MCE)

PXB17 can inhibit CSF1R (IC₅₀ = 1.7 nM) by blocking the activation of PI3K/ AKT/mTORC1 signaling. PXB17 is orally effective. PXB17 significantly inhibits the growth of CRC, improves PD-1 mAb efficacy and reduces tumor recurrence in CRC^[1].

Price Not Available 1 mg PXB17 | MedChemExpress (MCE) Supplier Page

Trivial name	PXB17
Catalog Number	HY-158050
Purity	≥98.0%
SMILES	CC1=C(C(C)=C(N1)/C=C2C(NC3=C\2C=CC(NC(NC4=NOC(C(C)(C)C)=C4)=O)=C3)=O)NC(CN5CCCC5)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/pxb17.html